Pen probe
Special electrical pulses are transmitted to the skin to create temporary openings in cell membranes.
Electroporation
MESONA-J
Mesona-J
Mesona-J
Gentle transdermal delivery for your skin
Needle-free delivery of selected skincare ingredients.
Care for multiple concerns at once, including dryness, dullness, redness, and visible pores.
Contents
CONCERNS
Mesona-J
Mesona-J
Concerns this treatment may address
Rather than targeting a single concern, this transdermal delivery treatment is designed to support the overall condition of the skin.
01Dryness and rough textureDry even if moisturizing
02Dullness and uneven toneThe entire face looks dark
03Redness and sensitivityI want to avoid strong stimulation treatment
04Aiming for a smooth texture
05Loss of firmnessDrying wrinkles
06Combination careI would like to consult a post-laser care
ABOUT MESONA-J
About Mesona-J
NEEDLE-FREE DELIVERY
without needles
without needles
Deliver skincare ingredients to your skin
Mesona-J is a transdermal delivery device developed in Japan for use in medical clinics. Its mesoporation method uses specialized electrical pulses to deliver skincare ingredients applied to the skin surface.
Treatment uses two probes: a pen-type probe and a roller-type probe. No skin-penetrating needles are used, and multiple ingredients can be combined according to the patient's concerns.
- A medical-clinic device developed and manufactured in Japan
- Compliant with quality standards such as JIS and EMC testing
- Treats the full face and neck
MECHANISM
Two processes
Two processes
Introduction of Mesona-J
First, the pen probe prepares temporary pathways for the skincare ingredients; the roller probe then distributes them carefully over the treatment area.
Roller type probe
We introduce skincare ingredients to the skin using electrical repulsion, electro-osmotic force, and gentle physical pressure.
Electronic
INGREDIENTS
For skin growth
For skin growth
Mesona-J fees
Customize
Used for injections
High-purity ingredients intended for medical use
High-purity ingredients intended for medical use
Selected ingredients address dryness, dullness, redness, visible pores, reduced firmness, acne, and skin irritation.
OUR APPROACH
Our clinic's Mesona-J
Our clinic's Mesona-J
3 features
01
Full-face and neck treatment
Our standard treatment covers the full face and neck, helping maintain a consistent appearance across both areas.
02
High-purity ingredients intended for medical use
Ingredients are combined to address dryness, dullness, redness, pore concerns, reduced firmness, acne, and skin irritation.
03
For single treatment or combination care
Mesona-J may be used as regular stand-alone skin care or combined with care following another procedure such as ADVATx.
TREATMENT FLOW
Mesona-J treatment process
- 01
We ask about your skin concerns and explain the selected ingredients and treatment.
- 02
Cleansing and preparation
Makeup and sebum are removed to leave the skin clean and ready for ingredient delivery.
- 03
Pen probe
Electrical pulses prepare the skin for ingredient delivery.
- 04
Roller type probe
The customized solution is applied and delivered carefully over the full face and neck.
- 05
Finishing and aftercare
Treatment finishes with moisturizer and UV protection.
TREATMENT GUIDE
Treatment overview and precautions
Treatment rangeFull face and neck
PainIt is a treatment that does not involve strong pain. You can feel the feeling of electric stimulation and water.
DowntimeSignificant downtime is uncommon. Temporary redness, warmth, or irritation may occur.
Make-up & Face WashMakeup and face washing are permitted after treatment. Avoid rubbing the skin, moisturize it, and use sun protection.
Number of treatmentsOne-time care or five-time course.
Main adverse effectsRedness, hotness, itching, irritation, dryness, allergic reactions by the ingredients used, etc.
When treatment is contraindicated or requires caution
- Using embedded medical devices such as pacemakers
- Metal plates, gold threads, or other metal are present in the treatment area
- Pregnancy or possible pregnancy
- Severe dermatitis, infection, or an open wound is present in the treatment area
- Allergy to the ingredients used
Please let us know in advance.
Before your visit, tell us about current medical conditions, oral and topical medications, allergies, pregnancy or breastfeeding, and previous procedures on the face or neck.
Unapproved Medical Devices
- Unapproved Medical Devices
- Mesona-J is a medical device that has not been approved under Japan's Pharmaceuticals and Medical Devices Act.
- Access route
- Our clinic obtains the device through an authorized domestic distributor.
- Availability of an approved equivalent device in Japan
- No medical device with equivalent performance is approved in Japan.
- Safety information in foreign countries
- No established information has been confirmed regarding overseas approval status or serious risks.
Treatment using an unapproved medical device may not be covered by Japan's Relief System for Sufferers from Adverse Drug Reactions.
PRICE
Mesona-J fees
Mesona-JFull face and neck
1 time¥20,000
5 times¥90,000
In case of receiving with ADVATx¥18,000 per session
Self-pay treatment; tax included. Fees are current as of July 16, 2026. See the fee schedule for the latest prices.
FAQ
Mesona-J fees
Is Mesona-J painful?
It is a treatment that does not use needles and introduces skincare ingredients with electrical pulse and roller probes, which is generally well tolerated.
Can I apply makeup after treatment?
Makeup is permitted after treatment. Avoid rubbing the skin, moisturize it, and use sun protection.
What concerns can Mesona-J address?
Mesona-J may be suitable for people who want to address several concerns together, including dryness, dullness, redness, visible pores, reduced firmness, acne, and skin irritation.
Can I receive the same day as other treatments?
At our clinic, Mesona-J can be added after another procedure, such as ADVATx, when appropriate.
Can I receive Mesona-J?
Treatment is not available to people with an implanted medical device such as a pacemaker, metal in the treatment area, pregnancy, or severe active skin symptoms.
How many sessions are recommended?
Mesona-J may be used as a single skin-care session; a five-session course is also available for ongoing care.
CONSULTATION
from skin troubles
from skin troubles
Think of ingredients together
Ask us about Mesona-J as stand-alone skin care or in combination with another procedure such as ADVATx.
