ADVATx dual-wavelength laser
ADVATx 589 nm / 1,319 nm
ADVATx Laser is a laser that uses two wavelengths, 589 nm and 1,319 nm, to approach redness, inflammatory acne, redness of acne scars, sebum, pores, and firmness/gloss from a multifaceted perspective.
Content
Concerns that may be treated with ADVATx
The 589 nm and 1,319 nm wavelengths
The ADVATx laser uses a combination of 589 nm, which is involved in redness and blood vessel reactions, and 1,319 nm, which is involved in heat reactions in the sebaceous glands and dermis.
589 nm
This is a wavelength that easily reacts with hemoglobin. Effective for redness, telangiectasia, acne redness, and inflammatory skin conditions.
The diagram shows 589 nm laser energy being preferentially absorbed by hemoglobin. It illustrates treatment directed at visible redness, inflammation, and dilated capillaries while distinguishing the epidermis, dermis, and deeper tissue layers.
1,319 nm
This wavelength is used for the purpose of applying heat to fibroblasts and sebaceous glands in the dermis. Effective for improving sebum, pores, firmness/gloss, and skin quality.
The diagram shows 1,319 nm laser energy delivering a thermal effect to the dermis and sebaceous glands. This wavelength is considered when addressing sebum, visible pores, firmness, radiance, and overall skin quality.
How our clinic plans ADVATx treatment
Academic analysis and domestic and international knowledge
Average pain score: approximately 3–4/10, within a tolerable range. This is lower than the values shown for conventional treatment (5.3/10) and 1,726 nm treatment (4.9/10). The second bullet reports high patient satisfaction. A partial parenthetical is also visible: ‘in one study, patients—’.
No fee, treatment-course, or adverse-effect statement is printed in this slide.
The director serves as a key opinion leader for ADVATx, giving presentations at academic conferences, sharing settings with medical institutions, and interacting with overseas physicians. We reflect domestic and international knowledge in irradiation design.
Combined with spot irradiation at no additional charge
At the same time as ADVATx irradiation for the entire face, spot irradiation is performed on the necessary areas while identifying blood vessels and diseased areas at no additional charge.
No separate consultation fee for ADVATx visits
In order to make it easier for you to receive regular follow-up observations and follow-ups, ADVATx Treatment does not charge any additional consultation fees.
Inflammatory acne and post-acne redness
ADVATx laser is a laser that makes it easy to consider treatment plans from multiple angles, including not only inflammatory acne but also post-acne redness, sebum amount, and skin quality. In acne treatment, it is important not only to suppress inflammation, but also to reduce redness, regulate sebum, and improve skin quality.
Studies have shown greater improvement when lasers are combined with topical treatments for inflammatory acne. Additionally, for post-acne erythema, it has been reported that redness tends to improve relatively quickly and patient satisfaction is high.
Suitable for people who repeatedly suffer from inflammatory acne, those who tend to leave redness after acne, those who want to control redness and pigmentation, and those who want to combine external treatment with device treatment.
Inflammatory acne
Consider using it in conjunction with topical treatment for acne with redness, acne that is prone to reoccurrence, and conditions with excessive sebum.
Participants: 18 patients with inflammatory acne in a split-face comparative study. Treatment: topical benzoyl peroxide (BPO) over the full face plus a 589/1,319 nm laser on one side, four treatments at two-week intervals. Assessment: three-month follow-up.
Reduction in inflammatory-lesion count from baseline at three months: laser + BPO, 46% reduction; BPO alone, 29% reduction. The laser-combination side showed greater improvement, although the between-group difference was not statistically significant.
- Redness and pigmentation: patients with a greater decrease in acne also tended to show improvement in pigmentation.
- Skin unevenness and roughness: improvement was also observed.
- Safety: no serious adverse events were reported.
The percentages describe this study population and do not guarantee an individual result. No fee is printed in the figure.
Redness of acne scars
If redness remains even after the inflammation has subsided, consider the type of irradiation while looking at the vascular reaction and skin quality.
Participants: 29 patients with post-acne erythema in a split-face comparative study. Treatment: 589/1,319 nm laser on one side and aloe-vera (AV) gel on the other. Assessment: after six treatments with an eight-week follow-up; AV gel was applied twice daily for 18 weeks.
A. Improvement by at least one grade at week 8: laser side 72%; AV-gel side 69%. The percentage axis is marked 0%, 25%, 50%, 75%, and 100%. B. Speed of improvement: the laser side showed significant improvement from week 2; the AV-gel side from week 4. The laser side tended to improve sooner, but no between-group difference was shown at the final assessment.
- Relationship to acne: improvement in redness correlated with improvement in acne severity (rs = 0.47, p = 0.03).
- Patient satisfaction: tended to be higher on the laser side.
- Safety: no serious adverse events; pain was mild, with mean VAS 1.52/10.
These findings describe the study population and do not guarantee an individual result. No fee is printed in the figure.
References
Research on combination treatment for inflammatory acne
Boonpethkaew S, Anansiripun P, Maitrisathit W, Ratanapokasatit Y, Chirasuthat S, Wechsuruk P, Wattanakrai P. Efficacy and Safety of a Dual-Wavelength 589/1319 nm Laser for the Treatment of Acne Erythema: A Split-Face Randomized Controlled Trial. J Cosmet Dermatol. 2026;25(5):e70894. doi:10.1111/jocd.70894.
How skin aging develops
The skin is made up of two major layers: the epidermis and the dermis. The epidermis acts as a barrier to protect the skin from external stimuli and dryness, and the basal layer contains melanocytes that produce melanin. The dermis contains collagen, elastin, capillaries, immune cells, etc., and supports the skin's firmness, elasticity, complexion, and temperature regulation.
- Epidermis: stratum corneum, granular layer, spinous layer, and basal layer; the basement membrane lies beneath the basal layer, where melanocytes are also marked.
- Dermis: superficial and deep dermis, with capillaries shown among the fibers.
- Deeper layer: subcutaneous tissue below the dermis; the panel at left is an H&E-stained skin section.
Due to the effects of age, UV rays, friction, inflammation, etc., turnover in the epidermis decreases and melanin excretion tends to be delayed. Additionally, melanocytes become hypersensitive to stimuli, making melasma and pigmentation more likely to worsen. Furthermore, when the basement membrane that connects the epidermis and dermis becomes flattened, torn, or becomes multilayered, the barrier function decreases and the skin becomes susceptible to continued inflammation.
In the dermis, collagen and elastin production decreases due to decreased fibroblast function. On the other hand, decomposition progresses more easily and the dermis becomes thinner. As a result, the capillaries move closer to the surface, making redness more noticeable, the skin becoming less firm, and sagging more likely.
- Age 17: the basement membrane has a wavy, undulating contour.
- Age 87: the diagram labels flattening, breaks, and multilayering of the basement membrane; adherence of the stratum corneum; flattening and atrophy of the epidermis; basal-layer pigmentation; and solar degeneration in the dermis.
In other words, skin aging is not just a problem of age spots and sagging, but is also linked to redness, inflammation, melasma, and pigmentation. As fibroblast function declines, the dermis becomes thinner and the basement membrane and barrier function weaken, making it easier for micro-inflammation to continue. This inflammation leads to dilation of capillaries and stimulation of melanocytes, which can lead to chronic redness, melasma, and worsening of pigmentation.
From the epidermis and basement membrane through the dermis and subcutaneous fat, the diagram shows a possible cycle associated with aging and repeated stimulation: reduced fibroblast activity; reduced collagen and elastin production; loss of elasticity and thickness; dilated capillaries; chronic inflammation; and greater susceptibility to dullness and pigmentation.
Relationship between redness, melasma, and skin aging
Skin redness is not simply a matter of surface color, but reflects photoaging and chronic inflammation of the dermis. When the structure of the dermis changes due to the effects of ultraviolet rays, friction, aging, etc., capillaries tend to dilate, resulting in a skin condition where redness tends to persist.
Redness may reflect photoaging or chronic inflammation in the dermis. Ultraviolet exposure, friction, and aging can make capillaries more likely to dilate. The diagram labels the epidermis, dermis, and subcutaneous tissue and compares normal with dilated capillaries.
When examining age spots and melasma, it is important to not only look at the pigment, but also to check for redness and inflammation. In skin with strong redness, inflammation stimulates melanocytes and increases melanin production, making melasma and pigmentation more likely to worsen. Therefore, "pigment treatment" alone may not be sufficient for melasma. In addition to toning and whitening treatments, it is important to calm redness, inflammation, and telangiectasia, and prepare the foundation of the skin.
The arrows show this sequence: persistent redness and inflammation → stimulation of melanocytes → increased melanin → more visible melasma and pigmentation. Prolonged inflammation may make pigment concerns more persistent.
Rosacea and redness are associated with decreased skin barrier function, dilated capillaries, and chronic inflammation. Treatment may include a combination of skin care and lifestyle changes to avoid irritation, as well as treatments that target redness and inflammation.
- Pigment: address melanin production and deposition.
- Redness: address redness associated with dilated capillaries.
- Inflammation: reduce inflammation and support the skin environment.
- Skin foundation: support the condition of the dermis.
The four perspectives are considered together to improve overall balance; this may help treatment planning and recurrence prevention.
In the ADVATx laser, 589 nm is sensitive to hemoglobin and is used to treat redness, inflammation, and telangiectasia. For melasma with redness, redness on the face, redness from acne scars, etc., we consider treatment strategies that include not only pigment but also redness control. 1,319 nm stimulates fibroblasts, increases the production of skin collagen and elastin, strengthens the dermis, reduces inflammation and improves barrier function.
The 589 nm wavelength is readily absorbed by hemoglobin and may be used for redness, inflammation, and dilated capillaries. The diagram labels the epidermis, dermis, and subcutaneous tissue and illustrates selective treatment of a dilated capillary. Redness-associated melasma, facial redness, and post-acne erythema may be included in the treatment plan.
What is skin-quality treatment?
The diagram compares the skin foundation to soil and visible outcomes—brightness, firmness, smoothness, and refined texture—to fruit. Dry, hardened soil, insufficient nutrients, and nutrient imbalance are shown as conditions less likely to produce good results, emphasizing assessment and preparation of the skin foundation.
Hadaiku is a way of thinking that does not only focus on results such as whitening, firmness, smoothness, and fine texture, but also prepares the foundation of the skin that will produce those results. The materials compare skin to "soil" and changes such as whitening and firmness to "fruit." Just as it is difficult to grow good fruits in soil that is dry and hard, lacks nutrients, or is out of balance due to over-nutrition, it is important to assess the current condition of the skin and take care of it.
After examining the current skin condition, treatment may combine approaches that stimulate the dermis, such as laser or radiofrequency, with approaches that deliver selected ingredients, such as MESONA-J or injectable treatment. The sequence and combination depend on the findings.
Hadaiku combines ``cultivation treatment'', which applies moderate stimulation to the skin to elicit a response in the dermis, and ``nourishment treatment'', which delivers necessary ingredients to the skin. Lasers and high frequencies play the former role, while MESONA-J and injectable treatments play the latter role.
The diagram separates the epidermis and dermis. Purple cells represent fibroblasts, red fibers represent collagen, and blue fibers represent elastin. Fibroblasts participate in producing collagen and elastin and help maintain skin firmness; skin-quality treatment aims to support a healthier dermal structure.
The core that supports the foundation of the skin is the dermis. In the dermis, fibroblasts are involved in the production of collagen and elastin, supporting the firmness and elasticity of the skin. The goal of skin education is to revitalize these fibroblasts and restore a healthy dermis structure. ADVATx laser can be used to stimulate the dermis and fibroblasts through the thermal action of 1,319 nm, and is an option when considering improving skin quality, firmness, shine, pores, and sebum balance.
Around the goal of supporting the skin foundation, the diagram lists ADVATx, MESONA-J, injectable treatment, and ALLTITE radiofrequency treatment. The ADVATx panel specifically identifies the 1,319 nm wavelength and states that it is used with the aim of stimulating the dermis and fibroblasts. Whether to combine treatments, and their order and interval, are decided from the examination.
Skin-quality care may require more than one type of treatment. Depending on the skin condition and treatment goal, a plan may combine ADVATx, MESONA-J, injectable treatment, ALLTITE, or other appropriate options. Improved brightness or firmness may follow from addressing dermal condition, inflammation, dryness, sebum, and barrier function in a coordinated plan.
Case photos
The photographs are labeled Before then After in two views. Concern labels: melasma and acne. Course: follow-up after POTENZA melasma treatment plus five ADVATx laser sessions. Melasma around the eyes and enlarged pores were present when ADVATx treatment began. The creative states that melasma and chin acne improved and that 1,319 nm treatment supported rejuvenation, sebum control, and a change in skin texture.
The source image does not print a fee or risk statement. This is an individual case; the owner page states that results vary and that temporary redness, warmth, dryness, irritation, or hyperpigmentation may occur.
The photographs are labeled Before then After in two views. Concern labels: melasma and facial redness. Course: after five ADVATx laser sessions. Treatment began for diffuse facial redness with suspected melasma. The creative states that 589 nm treatment improved redness, melasma, and dilated capillaries around the nose, while 1,319 nm treatment controlled sebum and changed skin texture.
No fee or risk statement is printed in the image. This is an individual case; the owner page states that results vary and temporary redness, warmth, dryness, irritation, or hyperpigmentation may occur.
The photographs are labeled Before then After in two views. Concern label: redness around the nose. Course: after five ADVATx laser sessions. Dilated capillaries around the nose were treated. The creative states that, compared with Vbeam, treatment can be delivered in small millimeter-scale areas and is characterized by less pain and downtime.
No fee is printed in the image. This is an individual case and the comparison is descriptive, not a guarantee; the owner page notes that temporary redness, warmth, dryness, irritation, or hyperpigmentation may occur.
The photographs are labeled Before then After in two views. Concern label: acne. Course: after five ADVATx laser sessions. Before treatment there was redness and inflammatory acne. The creative states that overall redness improved and that controlling sebum was accompanied by fewer new acne lesions and less visible pores.
No fee or risk statement is printed in the image. This is an individual case; results vary and the owner page notes temporary redness, warmth, dryness, irritation, or hyperpigmentation as possible reactions.
The photographs are labeled Before then After in two views. Concern label: melasma. Course: after five ADVATx laser sessions. Age spots and melasma coexisted on the cheeks; because these require different treatment, melasma treatment was started first. ADVATx was delivered to the vascular redness beneath the melasma. The creative states that darker age spots remained while melasma improved.
No fee or risk statement is printed in the image. This is an individual case; results vary and the owner page notes temporary redness, warmth, dryness, irritation, or hyperpigmentation.
The photographs are labeled Before then After in two views. Concern label: melasma. Course: after two ADVATx laser sessions. Melasma and age spots coexisted on both cheeks. ADVATx was used first to treat melasma without aggravating it; the creative states that improvement was already visible after two sessions.
No fee or risk statement is printed in the image. This is an individual case; results vary and the owner page notes temporary redness, warmth, dryness, irritation, or hyperpigmentation.
The photographs are labeled Before then After in two views. Concern label: melasma. Course: after five Ruby fractional laser sessions and two ADVATx laser sessions. Melasma and age spots coexisted; Ruby fractional laser was delivered at lower output to avoid aggravating melasma, followed by ADVATx treatment. The creative states that darker spots and overall uneven tone were improving.
No fee or risk statement is printed in the image. This is an individual case; results vary and temporary redness, warmth, dryness, irritation, or hyperpigmentation may occur.
The photographs are labeled Before then After in two views. Concern label: redness. Course: after eight ADVATx laser sessions. The creative states that redness and sebum decreased and pores became less visible. It emphasizes that ADVATx addresses not only redness but also sebum.
No fee or risk statement is printed in the image. This is an individual case; results vary and the owner page notes temporary redness, warmth, dryness, irritation, or hyperpigmentation.
The photographs are labeled Before then After in two views. Concern label: melasma. Course: after two ADVATx laser sessions. The creative states that darker areas of melasma were lighter after two sessions and explains that melasma is associated with chronic inflammation, so treatment should avoid strong stimulation.
No fee or additional risk statement is printed in the image. This is an individual case; results vary and the owner page notes temporary redness, warmth, dryness, irritation, or hyperpigmentation.
The photographs are labeled Before then After in two views. Concern label: melasma. Course: five combined ADVATx laser and MESONA-J treatments. The MESONA-J solution contained 10 ingredients, including tranexamic acid, vitamin C, and glutathione, selected for melasma. The creative states that redness and uneven tone associated with melasma improved and that firmness increased and fine lines improved.
No fee or risk statement is printed in the image. This is an individual case; results vary and temporary redness, warmth, dryness, irritation, or hyperpigmentation may occur.
The photographs are labeled Before then After in two views. Concern label: acne. Course: after 10 ADVATx laser sessions. Treatment began for persistent acne, with vitamin A home care used concurrently. When acne was severe, insured incision-and-drainage treatment was also performed. The creative states that comedones and inflammatory acne decreased substantially.
No fee or risk statement is printed in the image. This is an individual case; results vary and temporary redness, warmth, dryness, irritation, or hyperpigmentation may occur.
The photographs are labeled Before then After in two views. Concern label: facial redness. Course: after four ADVATx laser sessions. Treatment began for diffuse facial redness. The creative states that overall redness improved, uneven tone became more balanced, and improvement in redness changed the overall impression.
No fee or risk statement is printed in the image. This is an individual case; results vary and temporary redness, warmth, dryness, irritation, or hyperpigmentation may occur.
ADVATx fees
The displayed price includes self-pay care and tax. Prices are consistent with the in-hospital price list as of July 17, 2026.
Acne, sebum, facial redness, melasma treatment
30,000yen
139,000yen
6,000yen
589 nm spot irradiation
6,600yen
4,400yen
MESONA-J combination option
18,000yen
ADVATx Laser
Treatment overview and precautions
- Treatment details
- The 589 nm and 1,319 nm wavelengths are delivered to target redness, inflammation, sebum, pores, skin quality.
- pain
- You may feel a sensation of heat or mild irritation. There are individual differences in how it feels.
- Downtime
- Temporary redness, warmth, swelling, dryness, or irritation may occur.
- After treatment
- Please moisturize and take measures against UV rays, and avoid friction and strong irritation.
- Main risks
- Redness, swelling, heat, dryness, irritation, pigmentation, blisters, burns, etc.
- If you cannot accept it
- If you are pregnant, have severe sunburn or dermatitis, or are using drugs that cause photosensitivity, you may not be able to receive the treatment.
About unapproved medical devices
The ADVATx used in this treatment is a medical device that has not been approved under the Pharmaceutical and Medical Device Act in Japan. At our clinic, we obtain these products through legal import procedures under the responsibility of our physicians. There may be cases where there is no approved medical device with the same performance in Japan. The manufacturer has announced that it has received clearance from the US FDA for multiple indications and is CE certified in Europe. Treatments using unapproved medical devices may not be covered by the Relief System for Adverse Drug Reactions.
Frequently asked questions about ADVATx
What is the ADVATx laser suitable for?
We will consider redness, telangiectasia, acne, redness of acne scars, sebum, pores, skin quality, and conditions where redness and inflammation are involved in melasma. Suitability will be confirmed during a medical examination.
How many times should I undergo acne treatment?
It depends on the situation. We will check your inflammatory acne, redness of acne scars, sebum level, skin care and external treatment status, and discuss the number of treatments while observing your reaction to each treatment.
Can I receive ADVATx laser even if I have melasma?
We will check the condition of the melasma, presence of redness or inflammation, and response to irritation during the examination. We consider treatment strategies that take into account not only pigment but also inflammation and vascular reactions.
Is there any downtime?
Temporary redness, warmth, dryness, etc. may occur. The course of treatment will vary depending on the symptoms and radiation content, so we will advise you of precautions during your consultation.
Can it be used in conjunction with MESONA-J and POTENZA?
Combination use may be considered depending on skin type, melasma, redness, and acne condition. The order and interval will be adjusted during your consultation to prevent stimulation from becoming too strong.
Consultation for redness, acne, melasma, and skin quality
Skin problems are often not just one problem, but a combination of redness, inflammation, pigment, sebum, and changes in the dermis. During your consultation, we will explain the suitability of ADVATx laser and its combination with other treatments.